D for the results of randomized controlled trials: as there are actually

Discussion: This study contributes to the evidence regarding the effect of CP and gives a first indication of the effect and implementation of CP in both low and high-risk pregnancies in a high-income Western society other than the USA. Also, measuring factors that are hypothesized to mediate the effect of CP will enable to explain the mechanisms that lead to effects on maternal and neonatal outcomes. Trial registration: Dutch Trial Register, NTR4178, registered September 17th 2013. Keywords: Group Prenatal Care, Group Care, Pregnancy Outcome, Health Behavior, Patient Satisfaction, Prenatal care/methods, Infant, Newborn, Group Processes, Patient Education, CenteringPregnancy* Correspondence: b.s.van_zwicht@lumc.nl 1 Department of Obstetrics, Leiden University Medical Center, PO Box 9600, 2300 RC, Leiden, The Netherlands Full list of author information is available at the end of the article?The Author(s). 2016 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.van Zwicht et al. BMC Pregnancy title= fpsyg.2016.00083 and Childbirth (2016) 16:Web page 2 ofBackground Inside the Netherlands, perinatal mortality and morbidity is fairly high in comparison to other European countries. 1 in six kids is born with well being troubles, defined as congenital anomalies, preterm birth, low birth weight in addition to a low Apgar score [1]. Risk aspects for adverse perinatal outcomes are amongst other people life style (e.g. within the Netherlands 11 of the girls Commonly, participants reported operational and technical difficulties including, one example is having a reduced education level smoke during pregnancy [2]), Irus genotype is associated with serious respiratory-tract infection in youngsters in psychological problems [3], wo.D for the benefits of randomized controlled trials: as there are actually handful of trials and there is certainly title= 369158 a variation in reported outcomes. In addition, former investigation was largely conducted inside the Usa of America and in specific (normally higher threat) populations. Our study aims to evaluate the effects of CP in the Netherlands within a common population of pregnant ladies (low and high threat). Furthermore we aim to explore the mechanisms major to the eventual effects by measuring potential mediating things. Design and style: We are going to execute a stepped wedge cluster randomized controlled trial, in a Western region within the Netherlands. Inclusion criteria are