Displayed important alterations in response to 3D COL1. ITGB1, ITGAV and

CTRL GO term Up-regulated by 3D COL1 right after 24h generation of precursor metabolites and power translational elongation oxidation reduction alcohol catabolic process glucose catabolic course of action Down-regulated by 3D COL1 following 24h mRNA metabolic course of action RNA processing regulation of cell cycle DNA metabolic method cell cycle Up-regulated by 3D COL1 after 48h translational elongation 1.19E-04 7 translational elongation amine catabolic Z-Ile-Glu-Pro-Phe-Ome biological activity procedure alcohol catabolic method glycolysis fructose metabolic procedure Down-regulated by 3D COL1 soon after 48h cell cycle regulation of cell cycle RNA processing mRNA metabolic course of action cell cycle process Up-regulated by 3D COL1 right after 72h alcohol catabolic procedure hexose metabolic method glucose catabolic process fructose metabolic course of action generation of precursor metabolites and energy Down-regulated by 3D COL1 soon after 72h RNA processing mRNA metabolic process RNA splicing response to organic substance regulation of cell cycle 5.25E-05 1.8E-04 0.00142 0.00309 0.00399 17 13 ten 16 ten RNA processing mRNA metabolic method RNA splicing DNA metabolic process cell cycle 9,52E-06 5,06E-05 5,44E-04 8,98E-04 0,00165 17 13 10 title= jcb.2011.23205 13 16 six.48E-04 0.0024 0.0028 0.0030 0.0041 5 6 4 three 7 alcohol catabolic course of action glycolysis glucose catabolic procedure hexose metabolic process hexose catabolic process three.36E-05 6.15E-05 1.41E-04 2.40E-04 two.77E-04 six 5 5 7 5 6.90E-06 1.20E-05 1.14E-04 1.65E-04 5.05E-04 26 16 19 15 18 RNA processing regulation of cell cycle cell cycle DNA metabolic procedure mRNA metabolic method 1.48E-05 1.61E-05 3.16E-05 5.81E-05 five.83E-05 21 16 25 19 16 7.50E-04 0.0022 0.0026 0.0044 0.0063 six 5 five four 3 1.65E-05 1.76E-05 four.66E-05 1.33E-04 2.76E-04 20 25 18 22 28 mRNA metabolic course of action regulation of cell cycle RNA processing RNA splicing DNA metabolic process 4.17E-06 4.27E-06 1.76E-05 6.14E-05 6.78E-05 18 17 21 14 19 3.04E-06 6.buy Hypericin 21E-06 two.63E-05 8.36E-05 9.97E-05 17 ten 23 eight 7 generation of precursor metabolites and power oxidation reduction glucose catabolic course of action hexose catabolic procedure monosaccharide catabolic procedure 1.07E-05 four.57E-04 six.96E-04 title= 1073858411404220 0.00133 0.00148 12 14 five 5 five p-value Gene count GO term MT1 p-value Gene countGenes modulated within the presence of 3D COL1 have been analysed by using the functional annotation tool of DAVID for functional enrichment evaluation, together with the DAVID default population background for Homo sapiens.Displayed significant alterations in response to 3D COL1. CTRL GO term Up-regulated by 3D COL1 after 24h generation of precursor metabolites and energy translational elongation oxidation reduction alcohol catabolic procedure glucose catabolic approach Down-regulated by 3D COL1 immediately after 24h mRNA metabolic approach RNA processing regulation of cell cycle DNA metabolic approach cell cycle Up-regulated by 3D COL1 after 48h translational elongation 1.19E-04 7 translational elongation amine catabolic method alcohol catabolic procedure glycolysis fructose metabolic course of action Down-regulated by 3D COL1 soon after 48h cell cycle regulation of cell cycle RNA processing mRNA metabolic approach cell cycle process Up-regulated by 3D COL1 soon after 72h alcohol catabolic approach hexose metabolic course of action glucose catabolic process fructose metabolic method generation of precursor metabolites and power Down-regulated by 3D COL1 soon after 72h RNA processing mRNA metabolic procedure RNA splicing response to organic substance regulation of cell cycle five.25E-05 1.8E-04 0.00142 0.00309 0.00399 17 13 10 16 10 RNA processing mRNA metabolic approach RNA splicing DNA metabolic method cell cycle 9,52E-06 five,06E-05 5,44E-04 eight,98E-04 0,00165 17 13 10 title= jcb.2011.23205 13 16 six.48E-04 0.0024 0.0028 0.0030 0.0041 five six 4 three 7 alcohol catabolic procedure glycolysis glucose catabolic course of action hexose metabolic procedure hexose catabolic process 3.36E-05 6.15E-05 1.41E-04 two.40E-04 two.77E-04 6 5 5 7 five six.90E-06 1.20E-05 1.14E-04 1.65E-04 5.05E-04 26 16 19 15 18 RNA processing regulation of cell cycle cell cycle DNA metabolic procedure mRNA metabolic course of action 1.48E-05 1.61E-05 3.16E-05 5.81E-05 5.83E-05 21 16 25 19 16 7.50E-04 0.0022 0.0026 0.0044 0.0063 6 five 5 4 3 1.65E-05 1.76E-05 4.66E-05 1.33E-04 two.76E-04 20 25 18 22 28 mRNA metabolic approach regulation of cell cycle RNA processing RNA splicing DNA metabolic course of action 4.17E-06 four.27E-06 1.76E-05 six.14E-05 six.78E-05 18 17 21 14 19 3.04E-06 6.21E-06 two.63E-05 8.36E-05 9.97E-05 17 ten 23 eight 7 generation of precursor metabolites and energy oxidation reduction glucose catabolic course of action hexose catabolic course of action monosaccharide catabolic procedure 1.07E-05 four.57E-04 6.96E-04 title= 1073858411404220 0.00133 0.00148 12 14 5 5 five p-value Gene count GO term MT1 p-value Gene countGenes modulated in the presence of 3D COL1 had been analysed by utilizing the functional annotation tool of DAVID for functional enrichment analysis, using the DAVID default population background for Homo sapiens.