Eable size without losing essential information through an orthogonal design (when

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Linguistically, the questions were adapted in the questionnaire for physicians from a self-assessment: "What would you choose ...?" into a judgment: "How do you think your patients would rate" and "What would your patient choose?".Statistical analysisThe Discrete Choice Experiment is a choice based method, and a variant of the conjoint analysis that was made possible through the theoretical work of Lancaster [16] and CUDC-427 site McFadden [17]. However, the problem of multiple testing has to be borne in mind: with more than 200 statistical tests to be performed some significant title= jir.2014.0026 results will be produced "by chance", they title= srep39151 are however artefacts (approx. 10 of such results must be expected at a 95 confidence level). A possible increase of significance level (e.g. Bonferroni correction) may minimize these errors but increases the risk of CUDC-907 biological activity ignoring really existing relationships. Therefore, a significance level of p