Displayed important alterations in response to 3D COL1. ITGB1, ITGAV and

CTRL GO term Up-regulated by 3D COL1 just after 24h generation of precursor metabolites and energy translational elongation oxidation reduction alcohol catabolic method glucose catabolic approach Down-regulated by 3D COL1 immediately after 24h mRNA metabolic course of Coproporphyrin III biological activity action RNA processing regulation of cell cycle DNA metabolic course of action cell cycle Up-regulated by 3D COL1 right after 48h translational elongation 1.19E-04 7 translational elongation amine catabolic approach alcohol catabolic order JNJ-42165279 process glycolysis fructose metabolic method Down-regulated by 3D COL1 just after 48h cell cycle regulation of cell cycle RNA processing mRNA metabolic approach cell cycle method Up-regulated by 3D COL1 following 72h alcohol catabolic procedure hexose metabolic procedure glucose catabolic procedure fructose metabolic method generation of precursor metabolites and energy Down-regulated by 3D COL1 after 72h RNA processing mRNA metabolic process RNA splicing response to organic substance regulation of cell cycle five.25E-05 1.8E-04 0.00142 0.00309 0.00399 17 13 ten 16 ten RNA processing mRNA metabolic procedure RNA splicing DNA metabolic procedure cell cycle 9,52E-06 5,06E-05 5,44E-04 eight,98E-04 0,00165 17 13 10 title= jcb.2011.23205 13 16 six.48E-04 0.0024 0.0028 0.0030 0.0041 five 6 4 three 7 alcohol catabolic procedure glycolysis glucose catabolic procedure hexose metabolic method hexose catabolic approach 3.36E-05 6.15E-05 1.41E-04 2.40E-04 two.77E-04 6 five five 7 5 6.90E-06 1.20E-05 1.14E-04 1.65E-04 5.05E-04 26 16 19 15 18 RNA processing regulation of cell cycle cell cycle DNA metabolic process mRNA metabolic process 1.48E-05 1.61E-05 three.16E-05 5.81E-05 5.83E-05 21 16 25 19 16 7.50E-04 0.0022 0.0026 0.0044 0.0063 6 five five 4 3 1.65E-05 1.76E-05 four.66E-05 1.33E-04 two.76E-04 20 25 18 22 28 mRNA metabolic approach regulation of cell cycle RNA processing RNA splicing DNA metabolic course of action 4.17E-06 four.27E-06 1.76E-05 six.14E-05 six.78E-05 18 17 21 14 19 three.04E-06 6.21E-06 2.63E-05 eight.36E-05 9.97E-05 17 ten 23 8 7 generation of precursor metabolites and power oxidation reduction glucose catabolic course of action hexose catabolic process monosaccharide catabolic course of action 1.07E-05 4.57E-04 six.96E-04 title= 1073858411404220 0.00133 0.00148 12 14 five five five p-value Gene count GO term MT1 p-value Gene countGenes modulated in the presence of 3D COL1 were analysed by using the functional annotation tool of DAVID for functional enrichment analysis, using the DAVID default population background for Homo sapiens.Displayed significant alterations in response to 3D COL1. The significance value connected with each Gene ontology term is really a measure of the likelihood that the association in between modulated transcripts as well as a provided term is due to random chance. The p-value was calculated utilizing the Fisher's Exact test. A total version of this table is out there as S2 Table.